Immunology is a rapidly evolving field of study that focuses on understanding how the immune system works and how it can be manipulated to prevent or treat diseases. Encompassing the entire field of immunology, this journal welcomes papers that investigate basic mechanisms of immune system development and function, with a particular emphasis given to the description of the clinical and immunological phenotype of human immune disorders, and on the definition of their molecular basis. Web Journal impact search engine. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Frontiers in Immunology has a current Impact Factor of 6.429, ranked 19th out of 184 journals in the Immunology category. J Immunol (1999) 163(1):2531. In this study, total B cells and immunoglobulin A increased after 90 days in flights and returned to baseline at return day. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). They are considered to be having more prestige in their respective fields, than those with lower values. Impact factors have been calculated yearly starting from 1975 for journals that are listed in the Journal Citation Reports (JCR). Annual Review of Immunology Annual Review of Immunology is a journal covering the categories related to Immunology (Q1); Immunology and Allergy (Q1). Libraries (125 pM) were multiplexed and sequenced with 100-base paired-end reads to a depth of ~50 million reads per sample using the Illumina NovaSeq 6000 System (Illumina, San Diego, CA, USA). Nat Med (2022) 28(1):5962. The latest impact index of the Frontiers in Immunology is 6.92. Reads were aligned to the publicly available human transcriptome and genome (GRCh38.84) using HISAT with default parameters (v2.0.13) (12). The impact factor must be used with primed peer review. In C1, seven of the top eight most enriched terms described immune system and leukocyte functions. What are Frontiers in Immunology Impact Factor? Citation frequencies for individual articles are quite diverse. Vol 238, Issue 4830. p. 1023. Given how much the use of journal impact factors has been increasing as well as how explicitly journal prestige is being used in research evaluation, it warrants a critical examination of this indicator. This study bears a number of limitations. Proceedings of the National Academy of Sciences of the United States of America Impact Factor, Frontiers in Immunology Publication Charges, Frontiers in Immunology Abstract & Indexing, Frontiers in Immunology SJR (SCImago Journal Rank), Journal impact factors do not statistically illustrate individual journal articles, Journal impact factors correspond terribly with real citations of individual articles, Authors use plenty of norms other than impact when theyre submitting to journals, Citations to non-citable items are sometimes incorrectly included in the database, If Self-citations exist, they are not corrected, Review articles are cited heavily and exaggerate the impact factor of journals, Lengthy articles have many citations and get high impact factors, Short publication time gap allows many short term journal self-citations and gives a fake high journal impact factor, Journals authors usually prefer citations in the national language of the journal, The database doesnt include books as a citation source, There is an English language bias with the database, American publications dominate the database, The impact factor is a function of the number of references per article in the research field, Research fields in which the content becomes swiftly obsolete are endorsed, The impact factor heavily depends on the extension or diminution of the field of research, High impact journals are tough to find in small research fields, The journal impact factor is strongly determined by relations between fields (clinical v basic research, for example), The citation rate of the article determines journal impact, but not vice versa which should be the case in the first place. The normalized read counts of gene candidates identified as differentially expressed between any of the 10 time points (temporal analysis) were averaged among all astronauts at each time point and scaled across genes as z-scores. In addition, we found 15,410 genes represented the expressed transcriptome of astronauts over all 10 time points and corresponded to genes with average normalized read counts >45 according to DESeq2s independent filtering threshold. doi: 10.1016/S0959-440X(00)00167-6, 46. Networks (B, E) illustrate semantic similarity of GO terms using REVIGO. Ratio of a journal's items, grouped in three years windows, that have been cited at least once vs. those not cited during the following year. Those studies offered valuable insight into the molecular interactions occurring during spaceflight but suffer from small astronaut sample sizes and lack an integrated time-dependent analysis. Transcriptional changes in circulating blood cells may thus reflect multisystem changes rich in information to assess astronaut health in response to the space environment and guide the design of personalized interventions. Expression of MEOX1 was comparable to FOXP3 in Treg cells and can be upregulated by IL-2. For topics on particular articles, maintain the dialogue through the usual channels with your editor. Our data on leukocytes transcriptome agree with the previous observations of transitional changes in immune cells while transitioning to and from space and the return toward baseline levels later after returning to Earth. The ISSN of Frontiers in Immunology is 16643224. WebLowest Journal's Impact IF (2011 - 2023) 0.809. Genome Res [Internet] (1971) 13(22):426. doi:10.1101/gr.1239303.metabolite, 24. Significant GO terms from the temporal gene clusters with >1.5 enrichment were displayed onto a dot plot. An opposite response occurs upon return to Earth; blood redistributes to the lower limbs, requiring an increase of total blood volume achieved by increasing fluid intake (6). Library quality was assessed using the Agilent BioAnalyzer 2100, and 72 samples passed the quality metrics for sequencing including a concentration above 10 nM (Supplementary Figure1). Alloimmunity and Transplantation Antigen. This resulted in samples with inadequate RNA quality for sequencing, which were rejected, leading to an unbalanced final sample size. doi:10.1038/s41526-020-00124-6, 33.
Top articles in 2017: Frontiers in Immunology Total Journal's Impact IF Growth Rate (2011 - 2023) 986.2%. IEEE Article Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and ballgown. Kozaki T, Takahama M, Misawa T, Matsuura Y, Akira S, Saitoh T. Role of zinc-finger anti-viral protein in host defense against sindbis virus. In addition to the 2-year Impact Factor, the 3-year Impact Factor, 4-year Impact Factor, 5-year Impact Factor, Real-Time Impact Factor can also provide further insights into the impact of Frontiers in Immunology. Wiley It is the frequency with which an average article in a journal has been cited in a particular year or period. 2017 has been a tremendous year of growth for Frontiers in Immunology the 5th-most cited of all journals in the category of Immunology, with an Impact Factor of 6.429. In this study, we investigated the effects of CB in the feed on growth performance, digestion and intestinal health of juvenile spotted sea bass. Universities and research institutions in Switzerland
doi: 10.1038/s41591-021-01637-7, 11. The best quartile for this journal is Q1. doi Received: 21 February 2023; Accepted: 18 May 2023;Published: 22 June 2023. doi: 10.1097/MAJ.0b013e318065b89b, 39. External citations are calculated by subtracting the number of self-citations from the total number of citations received by the journals documents. The relevance of the research to the field, The rigor of the study design and methodology, The potential impact of the research on scientific knowledge and clinical practice. Impact factor has many uses some of them are prominent but they can be misused too. Frontiers is well aware of the potential impact of published research both on future research and on society and, hence, does not support superficial review, light review or no-review publishing models. Citation: Stratis D, Trudel G, Rocheleau L, Pelchat M and Laneuville O (2023) The transcriptome response of astronaut leukocytes to long missions aboard the Crucian B, Simpson RJ, Mehta S, Stowe R, Chouker A, Hwang SA, et al. The other category includes miscellaneous RNA, pseudogenes,and RNA to be experimentally confirmed (TEC). New technique published in Frontiers in Robotics and AI allows artists to do just that. Relative gene expression levels for the profile of 15,410 expressed transcripts (genes with mean normalized read count >45) displayed as violin plots of scaled z-scores across time. Visitors may also download and forward articles subject to the citation requirements and subject to any fees Frontiers may charge for downloading licenses. ISO 4 (International Organization for Standardization 4) is an international standard that defines a uniform and consistent system for abbreviating serial publication titles and journals.
Impact Progress Report Treg cells, MEOX1, Foxp3, regulatory T cells, Omic analysis, human CD4. Oncol. This is a novel finding revealed through the temporal analysis. Technical limitations onboard the ISS hampered sample acquisition, processing, and analysis. Received: 24 Nov 2022;
This pattern was observed for the 276 temporally differentially expressed genes (Figure2) and was also evident with the profile of 15,410 genes obtained from independent filtering in DESeq2 (Supplementary Figure4). Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Informed and careful use of the data of impact factor is crucial. The two years line is equivalent to journal impact factor (Thomson Reuters) metric. (2008) 63(710):697705. Please include what you were doing when this page came up and the Cloudflare Ray ID found at the bottom of this page. The Frontiers in Immunology IF measures the mean of citations obtained in a particular year 2021 by papers issued in the Frontiers in Immunology during the two preceding years 2021. Should a dispute arise, authors or reviewers can trigger an arbitration and will alert the Associate Editor, who can assign more reviewers and/or bring the dispute to the attention of the Chief Editor. This used the same GLM as in the temporal differential expression analysis but instead applied the Walds test on log2 fold changes (LFCs) for significance testing followed by LFC shrinkage using the ashr method (17). 9F008-140254). Citation: Lamouline A, Bersini S and Moretti M (2023) In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment. Samples were then plotted along PC1 and PC2 to visualize the variance explained by the individual astronauts and study time points. The Impact Factor of Frontiers in Immunology has steadily increased over the years, reflecting the growing importance of immunology research. Frontiers in Immunology is published by Frontiers Media S.A.. Your IP: In the past 9 years, this journal has recorded a range of SJR, with the highest being 3.034 in 2016 and the lowest being 2.021 in 2018. doi: 10.1038/npjmgrav.2015.13, 9. Methods: Fourteen male and female astronauts with ~6-month- long missions aboard the International Space Station (ISS) had 10 blood samples collected throughout the three phases of the study: one pre-flight (PF), four in-flight (IF) while onboard the ISS, and five upon return to Earth (R). Briefly, the Euclidean distance between each gene candidate was calculated using their z-score scaled normalized read counts from each sample across time. WebFrontiers in Immunology. Figure2 Temporal analysis of leukocyte transcriptomes before, during, and after spaceflight. Our study also identified additional expression changes at phase transitions in genes unrelated to specific immune functions, such as cell population regulation. Under the Frontiers Conditions for Website Use and the Frontiers General Conditions for Authors, authors of articles published in Frontiers journals retain copyright on their articles, except for any third-party images and other materials added by Frontiers, which are subject to copyright of their respective owners. The Frontiers in Immunology encompasses the following areas: For a more comprehensive understanding of its scope, check the official website of this journal. Visit for all Journals Impact factor List. The impact score (IS), also denoted as Journal impact score (JIS), of an academic journal is a measure of the yearly average number of citations to recent articles published in that journal. WebThese findings in the context of CD4+ T cells contribute to a better understanding of the transcriptional networks and biological mechanisms controlling CD4+ T cell functionality, which opens new avenues for future therapeutic strategies. In the case of an academic evaluation for tenure, it is sometimes not considered appropriate to use the impact of the journal to calculate the expected frequency of a recently published article. Your email address will not be published.
Frontiers All authors participated in the critical revision of the article for important intellectual content. Innovation(China) [Internet] (2021) 2(3):100141. doi:10.1016/j.xinn.2021.100141, 22. As part of the temporal analysis, independent filtering of genes using DESeq2 excluded genes with mean normalized read counts <45 resulting in a profile of 15,410 genes representing the expressed transcriptome across time. Cell [Internet] (2020) 183(5):116284. Web Impact Factor. The calculation of the impact factor is seemingly easy. What are some of the latest trends and developments in immunology research? Patel ZS, Brunstetter TJ, Tarver WJ, Whitmire AM, Zwart SR, Smith SM, et al. The Frontiers platform enables post-publication commenting and discussions on papers and hence the possibility to critically evaluate articles even after the peer-review process. Chief Editors receive an honorarium if their specialty section or field reaches certain submission levels. Ground-based analogs for human spaceflight. This method increased power by assigning weights to each hypothesis test while controlling for the false discovery rate using the BenjaminiHochberg correction (16). ACM Your email address will not be published. This journal has an h-index of 190. Authors are therefore free to disseminate and re-publish their articles, subject to any requirements of third-party copyright owners and subject to the original publication being fully cited. The action you just performed triggered the security solution. doi: 10.3389/fphys.2019.00085, 27.
Frontiers Frontiers in Immunology is the official journal of the International Union of Immunological Societies (IUIS), PubMed, MEDLINE, PubMed Central (PMC), Scopus, Web of Science Science Citation Index Expanded (SCIE), Google Scholar, DOAJ, CrossRef, Chemical Abstracts Service (CAS), Embase, Semantic Scholar, Ulrich's Periodicals Directory, CLOCKSS, EBSCO, OpenAIRE, Zetoc. respective specialty section. Evaluating scientific quality is a notoriously difficult problem that has no standard solution.
Frontiers International Collaboration accounts for the articles that have been produced by researchers from several countries. Frontiers is fully compliant with open access mandates, by publishing its articles under the Creative Commons Attribution licence (CC-BY). This transcriptomic response is consistent with the head ward fluid shift and subsequent hemoconcentration of blood cells occurring when entering space (38). The journey to space and sojourn in this extreme environment expose astronauts to health hazards such as cosmic radiations and microgravity (1). (A) Gene expression levels plotted as scaled Z-scores across individual time points. doi:10.1016/j.cell.2020.10.050, 2. PloS One (2011) 6(7):e21800. The best quartile for the Frontiers in Immunology is Q1 (2022). Substantial gene expression changes at space transitions were dominated by genes downregulated during early spaceflight (IF2) and upregulated during the return to Earth (R1). It's publishing house is located in Switzerland. The next characteristic of leukocyte transcriptome temporal changes observed was the transcriptional convergence toward average levels displaying no differential expression after 2 months of space exposure. At transition from space to Earth, transcriptomes were characterized by an up regulation of expression, opposite to changes measured when reaching space. Gene read counts for the 59,901 genes from each sample were normalized for sample read depth using DESeq2s median of ratios (14), and the variance stabilizing log2 transformation (VST) was applied reducing variance of low read counts for principal component analysis. 37.187.182.66 Front Physiol (2020) 11(June):16. The organization or individual who handles the printing and distribution of printed or digital publications is known as Publisher. PLOS One Updated Impact Factor List. * Required, Email(will not be published)
The entire calculation of the impact factor is based on a two-year period and consists of dividing the number of times that articles were cited by the number of articles that are citable. Fourteen astronauts, 11 men (46.7 7.3 years old) and three women (39.7 2.1 years old) consented to participating in the study on the temporal analysis of the leukocyte transcriptomes from blood samples collected throughout the three phases of their mission: pre-flight (PF), in-flight (IF), and return to Earth (R). doi:10.1016/j.resp.2009.07.005, 7. Our analysis at both transition to a different gravitational environment revealed novel genes and pathways not previously documented in astronauts traveling to space. The latest h-index of the Frontiers in Immunology is 190. doi:10.1126/science.6729477, 10. Copyright notices must be displayed prominently and may not be obliterated, deleted or hidden, totally or partially. 9h.
Frontiers in Immunology Latest Journal's Impact IF 2022 As our understanding of the immune system and its role in health and disease continues to evolve, we expect many exciting discoveries and advancements. The Frontiers in Immunology is currently ranked 1297 out of 27955 Journals, Conferences, and Book Series in the latest ranking. In contrast, C2 was composed of terms describing diverse biological processes including anatomical structure and development and molecular regulation such as DNA-binding transcription factor (Figure2). Requests to access the datasets should be directed to the corresponding author/s. Terms with >1.5 enrichment in each temporal cluster were plotted with the number of genes mapping to that specific GO term indicated in brackets. All 139 samples had RNA integrity number (RIN) 8.0. Controlling the false discovery rate: a practical and powerful approach to multiple testing. Epigenetic analyses revealed a permissive epigenetic landscape for MEOX1 solely in Treg cells. We measured gene expression through RNA sequencing of leukocytes and applied generalized linear modeling to assess differential expression across all 10 time points followed by the analysis of selected time points and functional enrichment of changing genes to identify shifts in biological processes. Enrichment analysis of the 112 downregulated genes between PF and IF2 and 135 upregulated genes between IF4 and R1 identified biological functions differing between the transitions to and from space. Shown in a dot plot are the GO terms from each temporal gene cluster with an enrichment >1.5 (Figure2). The biological meaning is unclear but indicative of global mechanisms yet to be identified that limit variations of mRNA levels in leukocytes in space. WebFrontiers in Materials - Impact Factor & Score 2023 | Research.com Frontiers in Materials Research Impact Score* 4.5 OFFICIAL WEBSITE Ranking & Metrics Research Impact Score*: 4.5 Impact Factor: 3.985 Citescore: 3.7 SCIMAGO SJR: 0.664 SCIMAGO H-index: 32 Research Ranking (Materials Science) 229 Research Ranking (Engineering and The standard ISO4 abbreviation for the Frontiers in Immunology is Front. WebFrontiers in Immunology is a leading journal in its field, publishing rigorously peer-reviewed research across basic, translational and clinical immunology. *Correspondence: Odette Laneuville, olaneuvi@uottawa.ca, Artificial intelligence in predicting, determining and controlling cell phenotype or tissue function in inflammatory diseases, View all
B cell homeostasis is maintained during long-duration spaceflight. Cell Mol Life Sci [Internet] (2022) 79(9):116. doi: 10.3174/ajnr.A6249, 3. We sought to characterize the molecular response involved by capturing changes in leukocyte transcriptomes from astronauts transitioning to and from long-duration spaceflight. 14:1171103. doi: 10.3389/fimmu.2023.1171103. FASEB J (2020) 34(12):1614462. The h-index is defined as the maximum value of h such that the given journal/author has published h papers that have each been cited at least h number of times. In conclusion, the Frontiers in Immunology Impact Factor is an important metric that measures the relative importance and influence of the journal within the field of immunology research. Web 13 rows Immunology Impact Factor IF number of article detailed information and journal factor. By performing reverse network engineering, we identified six common denominators of CD4+ T cell functionality (CREB1, E2F3, AHR, STAT1, NFAT5 and NFATC3). Read the full analysis here. If your research field is/are related to Immunology (Q1); Immunology and Allergy (Q1), then Frontiers in Immunology continues to rank among the worlds top immunology journals in terms of influence and quality, as shown by our analysis of the Demontis GC, Germani MM, Caiani EG, Barravecchia I, Passino C, Angeloni D. Human pathophysiological adaptations to the space environment.
Anders S, Pyl PT, Huber W. HTSeq-a Python framework to work with high-throughput sequencing data. Front. Frontiers in Immunologyis a leading journal in its field, publishing rigorously peer-reviewed research across basic, translational and clinical immunology. 2022 www.resurchify.com All Rights Reserved. * Correspondence:
That is why Frontiers provides online free and open access to all of its research publications. Frontiers in Immunology is the official journal of the International Union of Immunological Societies (IUIS). The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1171103/full#supplementary-material. doi:10.1038/nprot.2009.97, 19. Elsevier
Frontiers Frontiers in Immunology | Comparative Immunology Many immune alterations persist during long-duration spaceflight (8). If we assume that the journal is illustrative of its articles, the journal impact factors of an authors articles can be used as a representative to get an objective understanding and quantitative measure of the authors scientific achievements. The Associate Editor assesses the reviews and activates the Interactive Review informing the authors of the extent of revisions that are required to address the reviewers comments, and starting the Interactive Discussion Forum where authors and also the reviewers get full access to all review reports. WebPart of the largest and most cited immunology journal, focusing on vaccines and molecular therapeutics against well-known and emerging pathogens that challenge human or Frontiers in Immunologyis the official Journal of theInternational Union of Immunological Societies (IUIS). Figure1 Experimental design. Name
Sec. New Research: Clinical experience and safety of Janus kinase inhibitors in giant cell arteritis: a retrospective case The notable modulation of transcription factors (ZNF and CD) and lncRNAs that regulate expression of downstream target genes may explain why the same differentially expressed genes are regulating different physiological responses.
Journal impact: Frontiers in Immunology A suppression of blood cell proliferation represents an adaptation to the reduced blood volume in space. WebThese findings in the context of CD4+ T cells contribute to a better understanding of the transcriptional networks and biological mechanisms controlling CD4+ T cell functionality, Frontiers' philosophy is that all research is for the benefit of humankind. Common misconceptions about Impact Factor include the idea that it measures the quality of individual articles or authors rather than the journal. EMBO J (1994) 13(9):215666. Asterisk (*) in bar plots (A, D) indicate the genes use in the enrichment analysis. Late IF time points corresponding to IF3 and IF4 had the lowest IQRs compared to all 10 time points (0.29 and 0.32, respectively) (Supplementary Table1). B = the total number of citations published during 2020 and 2021. It is used for the recognition of journals, newspapers, periodicals, and magazines in all kind of forms, be it print-media or electronic. Of the 112 genes downregulated early IF, 100 (89.3%) of those same genes were upregulated immediately upon return to Earth. In the current study, we took advantage of the rare opportunity to sample a cohort of 14 astronauts onboard the ISS for ~6-month missions. Borroto A, Lama J, Niedergang F, Dautry-Varsat A, Alarcon B, Alcover A. No use, distribution or reproduction is permitted which does not comply with these terms. In addition, a potential contribution of altered leukocyte subpopulations to gene differential expression can not be excluded. The Venn diagram (A) indicates the profile of genes being displayed in the heatmap (B). Ideally, published scientific results should be inspected by real experts in the field and should be given scores for quality and quantity according to the rules established. Zinc Finger proteins are transcriptions factors that have a wide range of molecular functions including DNA recognition, RNA packaging, transcriptional activation, regulation of apoptosis, protein folding and assembly, and lipid binding (45).
Frontiers doi: 10.1002/ajh.25699, 40. Current Frontiers in Immunology Impact Factor and Ranking. Transiting to and from microgravity was associated with the differential expression of 120 and 151 genes from the reference list of 15,410 genes expressed in leukocytes.
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