In immobile patients and infants, the Fowler's position alleviates compression of the chest that occurs due to gravity. The direction and magnitude of treatment effects were consistent between studies, but the metaanalysis was based only on data from 19 participants (see Table 3). Zuege D. Kinetic bed therapy to prevent nosocomial pneumonia in mechanically ventilated patients: a systematic review and metaanalysis, The effects of positioning on hemodynamics and gas exchange in the critically ill: a review. In the absence of sufficient washout between treatments, an optimal (uniformity and balanced) crossover design may account for the presence of carryover effects if period effects and treatmentbyperiod interactions are ruled out (Jones 2003; Senn 2002). D. Trial is located in a critical care area (e.g. Managing data for the review: NH. thesis, University of Manchester, Manchester, United Kingdom, Body position and ventilationperfusion relationships in unilateral pulmonary disease, Reproducibility and accuracy of pulmonary artery pressure measurements in supine and lateral positions, Multisite randomized clinical trial of horizontal positioning to prevent and treat pulmonary complications in mechanically ventilated critically ill patients: hemodynamic substudy, Southern Online Journal of Nursing Research. In addition, clinical adverse events reported as dichotomous or continuous data within the metaanalysis were intended to be grouped for narrative analysis according to the following classification of severity adapted from Vohra 2007: severe (unintentional event or complication that is associated with morbidity and mortality), moderate (unintentional event or complication requiring immediate medical intervention but not directly associated with morbidity and mortality) and mild (self limiting event or complication that is transient in nature, requiring no medical intervention). One study (de Laat 2007) introduced a nonrandomized group after study commencement, and this invalidated data extraction. Routine positioning usually involves moving the patient between right and left lateral positions. No muscle relaxants given and no change in vasoactive medication dose rates, 45 degrees lateral rotation, passively turned with participants instructed not to assist, commercial foam wedge to maintain angle, 15minute stabilization period (data collected over 5 minutes before next position change), Post hoc power analysis performed (effect size 0.558 to detect mean difference in CaO, Computergenerated randomized positioning sequence. Schaefer K, Each study reported a small MD between lateral positions during early turning responses (up to 10 minutes), which lacked precision (Lewis 1997; Reed 2002) (see Table 8.6, Appendix 8). We conducted very limited quantitative analysis and found lowquality evidence of the effects of lateral positions on partial pressure of arterial oxygen (PaO2) as a measure to detect hypoxaemia in two small studies (Ibanez 1981; Remolina 1981). Therefore, knowledge of group assignment during the study was unlikely to lead to plausible outcome assessor bias. Similar issues of inadequate outcome reporting of withinsubject effects as well as inconsistencies in reporting study procedures for minimizing bias were prominent in this systematic review of crossover studies providing more than two treatments. To relieve abdominal pain and ease breathing. Number of excluded participants (i.e. Twohourly turns are standard practice for prevention of complications associated with prolonged bed rest (Ahrens 2004; Doering 1993; Krishnagopalan 2002). This position is ideal for excretion. Standard management may not have been equally applied across groups and periods, as titration of vasoactive medications/fluids, use of PRBC and volume expanders were not controlled for, 34 mechanically ventilated adults who were haemodynamically stable (baseline HR 60 to 130 beats/min, MABP 70 to 120 mmHg, no compromising arrhythmias, ICP < 20 mmHg, mean PAP < 30 mmHg, PCWP 8 to 17 mmHg) and met subgroup classification, Left lateral and right lateral positions for 120 minutes, first supine position for 60 minutes, second supine position for 30 minutes, (1) P/F ratio, (2) MABP and HR, (3) CO and CI (BilatLP subgroup only), (4) adverse events, Ventilator settings constant (preplanned adjustment of FiO, 90 degrees lateral rotation, HOB elevation not described for lateral positions and < 20 degrees for supine position, angle verification method not described for rotation or HOB elevation, Sample size calculation for P/F ratio (20 in each group, moderate effect with magnitude of P/F change 20, = 35, = 0.05, 1 = 0.8). Seat-to-back-angle is where the seat support and the back support come together. Crossover designs require a sufficiently long washout between treatments to avoid the possibility that carryover effects may seriously influence the validity of effect estimates (Senn 2002). Six studies (n = 264) compared PaO2 between right lateral and left lateral positions (Banasik 1987; Banasik 1996; Banasik 2001; Chan 1992; Ibanez 1981; Kim 2002). Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: metaepidemiological study, The Cochrane Database of Systematic Reviews, National Pressure Ulcer Advisory Panel 2009, Characteristics of studies awaiting classification, The lateral position is described as sidelying with pillows strategically placed along the patient's back, and possibly buttocks, and a pillow placed between the patient's flexed legs to prevent adduction and internal rotation of the hip. Werken C. Pressure ulcers in intensive care patients: a review of risks and prevention. Semi-Fowler Position: What Is It, Difference from Fowler, and More As previously described, four studies (Bein 1996; Schellongowski 2007; Thomas 2007a; Tripathi 2009) did not perform valid pairwise comparisons involving supine position data. Participants randomized to sequences. Berman, A., Snyder, S. J., Levett-Jones, T., Dwyer, T., Hales, M., Harvey, N., & Stanley, D. (2018). The commonly used manual wheelchair models that are typically seen in the nursing home settings, due to the cheap upfront cost have a fixed 90-degree seat-to-back angle. 14. FOIA We retrieved fulltext reports for 160 selected citations, including several that included insufficient information in the title and/or abstract to enable a decision about relevancy. dopamine (n = 28), NTG (n = 25) and SNP), 30 degrees lateral rotation, 30 degrees hard foam, single pillow between legs, angle verification method not described, 30 minutes chosen as conservative rest period to allow for equalization of gases, Post hoc power calculation (effect size 0.2, 1 0.12, 0.05), power of 0.51 required a sample of 200 (stated to be beyond study scope), Not described. severity of illness (only trials with validated definitions, scales or scoring systems will be analysed for differences in findings due to differences in severity of illness); presence of assisted ventilation (for this review, assisted ventilation is considered to be any form of positive pressure, including noninvasive ventilation and continuous positive airway pressure (CPAP)); and. Nipride infusion (n = 18), 1 dose of morphine given during study (n = 18), decreasing use of intravenous nitrates throughout study, Degree of lateral rotation and angle verification method not described, No sample size calculation described. Eight studies provided some data; most of these were single studies with small effects that were imprecise. Stanton WR. The High Fowler's position is an upright medical position where the patient sits elevated with head and upper body raised at an angle between 60-90 in relation to the . Mean results did not reveal hypoxaemia (lowest mean PaO2 107 mmHg on right side (Ibanez 1981), 111.5 mmHg on left side (Banasik 1987)). We included trials with cointerventions applied equally across all groups. We pooled P/F ratio data for the comparison between bad lung down and good lung down in participants with unilateral lung disease, as we detected no statistically significant heterogeneity across composite time intervals (early turning response and shortterm turning response) (P value = 0.71, I2 = 0%) (Analysis 1.2). Further research is required to assess the effects of lateral positioning as a simple, inexpensive and easy to execute positioning practice compared with other positioning schedules (semi recumbent positioning and prone positioning) on respiratory outcomes such as acute lung injury (ALI), ventilatorassociated pneumonia (VAP) and severe atelectasis (involving several segments of a lung lobe or the whole lobe with associated opacification and loss of lung volume on chest radiograph) and mortality. In contrast, this systematic review has considered the appropriate unit of analysis for extracting data from crossover studies (i.e. Other preplanned summary statistics of effect included risk ratio (RR) for dichotomous outcomes and standardized mean difference (SMD) for different continuous outcome scales across trials. Pfeifer M, Altman DG, Coyle B, Routine lateral repositioning is a relatively safe standard practice. hOutcome measures include cardiac output (CO) less than 4 L/min, cardiac index (CI) less than 2.2 L/min/m2 and low arterial oxygen content (CaO2) (critical thresholds for detecting low DO2) bSupine position data were not combined with baseline supine data as conducted in the original study, 4.9 MD in PaO2(mmHg) with 95% CI (GIV, REM) between supine position (S) and right lateral (R) position during a shortterm turning response, 4.10 MD in PaO2 (mmHg) with 95% CI (GIV, REM) between supine position (S) and bad lung down (BLD) for unilateral lung disease participants during a shortterm turning response, Footnotes: aTreatment effect estimate calculated from individual participant data. The total duration of the positioning schedule and the time spent in each body position may vary between trials, Profound hypertension (severe, refractory or hypertensive crisis), Mean DBP 120 mmHg, or any definition given by investigators, Low oxygen delivery (single determinants), Mean CO < 4 L/min or mean CI < 2.2 L/min/m, Global indicator of tissue oxygenation impairment (imbalance between oxygen supply vs demand), Studies could not be pooled because of variability and incomplete data reporting for metaanalysis, Studies had incomplete data reporting for metaanalysis, Sample data not available from single crossover study, Editorial team changed to Cochrane Emergency and Critical Care, (MH:exp=Critical Care) or (MH:exp=Life Support Care) or (MH:exp=Critical Illness) or (TS="critical care") or (TS="intensive care") or (TS="coronary care") or (TS="cardiothoracic unit") or (TS=( ICU or ITU or CCU or CTU )) or (TS="critical* ill*"), (MH:exp=Respiration, Artificial) or (MH:exp=Ventilators, Mechanical) or (TS="artificial* respirat*") or (TS="mechanical* ventilat*") or (TS="positive pressure ventilat*") or (TS="non invasive ventilat*"), (TS="lateral position*") or (TS= "lateral rotat*") or (TS= "lateral recumben*") or (TS= "lateral turn*") or (TS= "lateral decubit*") or (TS= "lateral tilt*") or (TS="side lying") or (TS= "side position*") or ((TI=lateral or AB=lateral) and MH:exp=Posture) or (TI="dependent position*" or AB="dependent position*"), (MH=Prone Position) or (MH=Supine Position) or (MH=Headdown Tilt) or (TS="supine position*") or (TS="dorsal position*") or (TS=recumben*) or (TS="horizontal position*") or (TS="prone position*") or (TS="ventral decubit*") or (TS="head down*") or (TS="head tilt*") or (TS=Trendelenburg) or (TS="vertical position*") or (TS="degree* position*") or (TS="backrest elevat*") or (TS= "head elevat*") or (TS=(semiFowler* or Fowler*)) or (TS=(semirecumben* or semirecumben*)) or (TS=sitting) or (TS="upright position*") or ((TI= position* or AB= position*) and MH:exp=Posture), (#7) AND Document Types=(Randomized Controlled Trial), (MH=(randomized controlled trials) OR MH=(Random Allocation) OR MH=(Double Blind Method) OR MH=(Single Blind Method)), ((MH:exp= Clinical Trials) or (TI= (clin* SAME trial*)) or (AB=(clin* SAME trial*)) or (TI=((singl* or doubl* or trebl* or tripl*) SAME (blind* or mask*))) or (AB=((singl* or doubl* or trebl* or tripl*) SAME (blind* or mask*))) or (MH=Placebos) or (TI=placebo* or AB=placebo*) or (TI=random* or AB=random*) or (MH=Research Design)), (MH=Comparative Study) or (MH:exp=Evaluation studies) or (MH=Follow Up Studies) or (MH=Prospective Studies) or (TI=(control* or prospectiv* or volunteer*) or AB=(control* or prospectiv* or volunteer*)), MeSH descriptor: [Critical Care] explode all trees, MeSH descriptor: [Life Support Care] this term only, MeSH descriptor: [Critical Illness] this term only, (critical care) or (intensive care) or (coronary care) or (cardiothoracic unit) or (ICU or ITU or CCU or CTU) or (critical* ill*), MeSH descriptor: [Respiration, Artificial] this term only, MeSH descriptor: [Ventilators, Mechanical] explode all trees, (artificial* respirat*) or (mechanical* ventilat*) or (positive pressure ventilat*) or (non invasive ventilat*), #1 or #2 or #3 or #4 or #5 or #6 or #7 in Trials, (lateral position*) or (lateral rotat*) or (lateral recumben*) or (lateral turn*) or (lateral decubit*) or (lateral tilt) or (side lying) or (side position*) or (dependent position*), MeSH descriptor: [Posture] explode all trees, MeSH descriptor: [Prone Position] this term only, MeSH descriptor: [Supine Position] this term only, MeSH descriptor: [HeadDown Tilt] this term only, (supine position) or (dorsal position) or (recumbent*) or (horizontal position*) or (prone position) or (ventral decubuit*) or (head down*) or (head tilt*) or (Trendelenburg) or (vertical position*) or (degree* position*) or (backrest elevat*) or (head elevat*) or ((semiFowler*) or (Fowler*)) or ((semirecumben*) or (semirecumben*)) or (sitting) or (upright position*), #13 or #14 or #15 or #16 or #17 in Trials, (MH "Critical Care+") or (MH "Critical Care Nursing+") or (MH "Life Support Care") or (MH "Critical Illness") or (MH "Critically Ill Patients") or (MH "Intensive Care Units+") or "critical care" or "intensive care" or "coronary care" or "cardiothoracic unit" or (ICU or ITU or CCU or CTU) or "critical* ill*", (MH "Ventilation, Mechanical+") or "mechanical ventilat*" or "artificial* respirat*" or "positive pressure ventilat*" or "noninvasive ventilat*" or "non invasive ventilat*", "lateral position*" or "lateral rotat*" or "lateral recumben*" or "lateral turn*" or "lateral decubit*" or "lateral tilt*" or "side lying" or "side position*" or ((TI lateral or AB lateral) and MH "POSTURE+") or ((TI lateral or AB lateral ) and MH "Patient Positioning") or ((TI dependent position* or AB dependent position*)), (MH "Patient Positioning+") or "supine position*" or "dorsal position*" or recumben* or "horizontal position*" or "prone position*" or "ventral decubit*" or "head down*" or "head tilt*" or Trendelenburg or "vertical position*" or degree* position* or "backrest elevat*" or "head elevat*" or semiFowler* or Fowler* or semi recumben* or semirecumben* or sitting or "upright position*" or ((TI position* or AB position*) and MH "POSTURE+"), (PT Clinical Trial) or "random* control* trial*" or (MH "Random Sample+") or (MH "DoubleBlind Studies") or (MH "SingleBlind Studies") or (MH "Clinical Trials+") or (TI clinical trial* or AB clinical trial*) or (TI (singl* or doubl* or trebl* or tripl*) and (blind* or mask*)) or (AB (singl* or doubl* or trebl* or tripl*) and (blind* or mask*)) or (MH Placebos) or (TI placebo* or AB placebo*) or (TI random* or AB random*) or (MH "Quantitative Studies+") or (MH "Crossover Design") or (MH "QuasiExperimental Studies+") or (MH "Comparative Studies") or (MH "Evaluation Research") or (MH "Prospective Studies") or (TI (control* or prospectiv* or volunteer*) or AB (control* or prospectiv* or volunteer*)), (SU "Critical Care") or (SU "Intensive Care") or (SU "Intensive Care Units") or (SU "Coronary Care") or (SU "Life Support Care") or (SU "Critical Illness") or (TX "critical care") or (TX "intensive care") or (TX "coronary care") or (TX "cardiothoracic") or (TX (ICU or ITU or CCU or CTU)) or (TX "critical* ill*"), (SU "Ventilators Mechanical") or (SU "Respiration Artificial") or (TX "mechanical* ventilat*") or (TX "artificial* respirat*") or (TX "positive pressure ventilat*") or (TX "noninvasive ventilat*" or "non invasive ventilat*"), (TX "lateral position*") or (TX "lateral rotat*") or (TX "lateral recumben*") or (TX "lateral turn*") or (TX "lateral decubit*") or (TX "lateral tilt*") or (TX "side lying") or (TX "side position*") or (( TI "lateral" or AB "lateral" ) and SU "Posture") or (TI "dependent position*" or AB "dependent position*"), (SU "Prone Position") or (SU "Supine Position") or (SU "Headdown Tilt") or (TX "supine position*") or (TX "dorsal position*") or (TX "recumben*") or (TX "horizontal position*") or (TX "prone position*") or (TX "ventral decubit*") or (TX "head down*") or (TX "head tilt*") or (TX "Trendelenburg*") or (TX "vertical position*") or (TX "degree* position*") or (TX "backrest elevat*") or (TX "head elevat*") or (TX "Fowler*") or (TX "semi recumben*") or (TX "sitting") or (TX "upright position*") or (( TI position* or AB position* ) and SU "Posture"), (TS="critical care") or (TS="life support") or (TS="intensive care") or (TS="coronary care") or (TS="cardiothoracic unit") or (TS=(ICU or ITU or CCU or CTU)) or (TS="critical* ill*"), (TS="Respiration, Artificial") or (TS="Ventilators, Mechanical") or (TS="artificial* respirat*") or (TS="mechanical* ventilat*") or (TS="positive pressure ventilat*") or (TS="non invasive ventilat*"), (TS="lateral position*") or (TS="lateral rotat*") or (TS="lateral recumben*") or (TS="lateral turn*" ) or (TS="lateral decubit*") or (TS="lateral tilt*") or (TS="side lying") or (TS="side position*") or (TS="lateral" and TS=Posture) or (TS="dependent position*"), (TS="prone position*") or (TS="supine position*") or (TS="head down tilt") or (TS="dorsal position*") or (TS= recumben*) or (TS="horizontal position*") or (TS="ventral decubit*" ) or (TS="head tilt") or (TS=Trendelenburg) or (TS="vertical position*") or (TS="degree* position*") or (TS="backrest elevat*") or (TS="head elevat*") or (TS=Fowler*) or (TS="semi recumben*" or TS="semirecumben*") or (TS=sitting) or (TS="upright position*") or (TS=position* and TS=Posture), (TS="random* control* trial*") or (TS="clinical trial*") or (TS=((singl* or doubl* or trebl* or tripl*) SAME (blind* or mask*))) or (TS=placebo*) or (TS=random*) or (TS=(control* or prospectiv* or volunteer*)), ((ti contains critical care) OR (ti contains intensive care) OR (ti contains critical* ill*) OR (ti contains ventilat*)) AND (ti contains lateral*), ((ti contains critical care) OR (ti contains intensive care) OR (ti contains critical* ill*) OR (ti contains ventilat*)) AND (ti contains position*), ((ti contains critical care) OR (ti contains intensive care) OR (ti contains critical* ill*) OR (ti contains ventilat*)) AND (ti contains turn*), ((ti contains critical care) OR (ti contains intensive care) OR (ti contains critical* ill*) OR (ti contains ventilat*)) AND (ti contains rotation*), ((ti contains critical care) OR (ti contains intensive care) OR (ti contains critical* ill*) OR (ti contains ventilat*)) AND (ti contains side lying), ((ti contains critical care) OR (ti contains intensive care) OR (ti contains critical* ill*) OR (ti contains ventilat*)) AND (ti contains postur*), ("critical care" and "lateral position*") or ("intensive care" and "lateral position*") or ("critical* ill*" and "lateral position*") or ("ventilat*" and "lateral position*"), ("critical care" and "lateral turn*") or ("intensive care" and "lateral turn*") or ("critical* ill*" and "lateral turn*") or ("ventilat*" and "lateral turn*"), ("critical care" and "lateral rotation*") or ("intensive care" and "lateral rotation*") or ("critical* ill*" and "lateral rotation*") or ("ventilat*" and "lateral rotation*"), ("critical care" and "side lying") or ("intensive care" and "side lying") or ("critical* ill*" and "side lying") or ("ventilat*" and "side lying"), ("critical care" and "body postur*") or ("intensive care" and "body postur*") or ("critical* ill*" and "body postur*") or ("ventilat*" and " body postur*"), Notes and changes after consensus agreement (recorded in red ink on primary reviewers form only), Right and/or left lateral position compared with other body positions (each body position maintained for 10 minutes), Trial includes mortality, morbidity or clinical adverse events as primary outcomes, or trial includes 1 secondary outcome.